Library & Information Science Research, a cross-disciplinary and refereed journal, focuses on the research process in library and information science, especially demonstrations of innovative methods and theoretical frameworks or unusual extensions or applications of well-known methods and tools. Library & Information Science Research publishes research articles primarily from a social science perspective.

LISR does not normally publish technical information science studies (e.g., algorithmic methods related to information retrieval or natural language processing) or most bibliometric studies, as these would find greater readership in the many fine journals covering these areas.

All papers are subject to a double-blind reviewing process.